Lab introduction & Blog
Recent advances in immuno-oncology point-out that not only cancer cells, but also the tumor microenvironment can guide precision medicine.Tumor microenvironment (TME) has been recognized to play important role of progression in multi-cancer.
1. To study the epigenetic regulation of immune cell for phenotypic switch in TME.
2. Drug discovery in the epigenetic regulation and new light in epi-drugs combination with other immunotherapy.
Exploring detailed mechanisms of T cell exhaustion in the cancer microenvironment
To verify cancer oncogenic mechanisms using the databases and clinical patients' tumor tissue sample to facilitate the development of novel drugs.
Exploring the treatment window of combination drugs :
to achieve the efficacy of subsequent immunotherapy by changing the cancer-immune microenvironment