Tumor
Microenvironment
Lab Introduction & Blog
Explore
the
science
Recent advances in immuno-oncology point-out that not only cancer cells, but also the tumor microenvironment can guide precision medicine.Tumor microenvironment (TME) has been recognized to play important role of progression in multi-cancer.
Research
-
Epigenetic regulation of immune cell for phenotypic switch in TME.
-
Drug discovery in the epigenetic regulation and new light in epi-drugs combination with other immunotherapy.
-
Exploring the impact of air pollution factor (PM2.5) on the development of lung cancer and its preventive mechanisms within the population with metabolic diseases.
-
Studies on the Association Between ALDH2 Gene Variants and Alcohol Intolerance in Esophageal Squamous Cell Carcinoma (ESCC).
Gene regulation
Exploring detailed mechanisms of T cell exhaustion in the cancer microenvironment
Clinical model
To verify cancer oncogenic mechanisms using the databases and clinical patients' tumor tissue sample to facilitate the development of novel drugs.
Drug development
Exploring the treatment window of combination drugs :
to achieve the efficacy of subsequent immunotherapy by changing the cancer-immune microenvironment